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Determining the system of action (MOA) of novel or naturally occurring compounds mainly relies on assays tailor-made for personal target proteins. Here we take a look at an alternate technique depending on pattern matching reaction profiles acquired employing cultured neuronal networks. Conolidine and cannabidiol are plant-derivatives with recognis
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Damage to peripheral nerve is often due to compression and reducing and through a variety of trauma, or ischemic and metabolic Conditions. This creates a condition of neuropathic pain, characterized by a rise in painful sensitivity, for instance hyperalgesia and allodynia. In addition, the compression from the peripheral nerves is frequently also a